Ep.80 – Exploring the Microbiome: Pertinent details from a phase 1 study exploring omadacycline in healthy guts

Episode Notes

In this episode, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard is joined by Dr. Kevin Garey, an adjunct professor at the University of Texas School of Public Health and senior author of the reviewed article. They walk us through the details of the microbiome effects oral omadacycline has versus oral vancomycin and what this might mean for the future of the treatment for C. difficile infections. The materials reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38051631/ and https://pubmed.ncbi.nlm.nih.gov/22563022/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.79 – It’s All in the Dose: High-dose oral beta-lactams for bacteremic UTIs due to Enterobacterales

Episode Notes

In this episode, DASON Clinical Pharmacist Liaisons Drs. Melissa Johnson and Jeannette Bouchard discuss an article from ASHE on high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/37771747/

For more information about DSAON, please visit: https://dason.medicine.duke.edu/

Ep.78 – Source Specific Sepsis Order Sets Lead to Improved Empiric Therapy in the ED

Episode Notes

In this episode, Dr. April Dyer, one of our DASON Clinical Pharmacist Liaisons, talks to us about source specific order sets leading to improved empiric therapy in the ED in a 200 bed hospital. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad677/7491622#

To learn more about DASON, please visit: https://dason.medicine.duke.edu

Ep.75 – Febrile Podcast: Being a Stewie

Episode Notes

This week we would like to use the feed to share a great episode of Sara Dong's podcast "Febrile."  Members of our DASON team and the Society for Healthcare Epidemiology of America's antimicrobial stewardship committee celebrate antibiotic awareness week by discussing stewardship teams and an example case.

Ep.74 – Neurotoxicity vs Nephrotoxicity: A Look at the Comparative Safety of Cefepime and Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection

Episode Notes

In this episode, Dr. April Dyer, one of the DASON Clinical Pharmacists, talks about cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37837651/

For more information about DASON, please visit: https://dason.medicine.duke.edu

Ep.72 – Hit me with your best shot! Tools to select the best empiric therapy in complicated UTIs

Episode Notes

In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard talks to us about clinical risk scores to improve empiric antimicrobial selection for outpatient complicated urinary tract infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/8/ofad319/7198038#413122181

For more information about DASON, please visit: https://dason.medicine.duke.edu

2020