DASON Digest

Ep.87 – BCI(De-escalation): The Impact of Rapid Diagnostics and Stewardship Intervention on Treatment of Contaminated Blood Cultures

Episode Notes

In this episode, University of Kentucky Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, review a recently published article evaluating the impact of the implementation of rapid blood culture identification technology and stewardship intervention on treatment of blood cultures contaminated with coagulase-negative staphylococci. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/8/ofad416/7233915

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.86 – PEN-FAST and Furious: The efficacy of the PEN-FAST tool in de-labeling previously reported penicillin allergies

Episode Notes

In this episode, University of Kentucky PGY2 Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, discuss the recently published article evaluating the efficacy of the clinical decision tool, PEN-FAST, in de-labeling patients with reported penicillin allergies with one of the authors and Duke University Hospital Infectious Diseases Physicians, Dr. Nick Turner. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37459086/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.85 – The devil's in the defaults: the impact of eliminating default durations of therapy

Episode Notes

In this episode, Duke University Hospital Infectious Diseases Pharmacist Dr. Rebekah Wrenn and her resident, Amy Mackowiak, review Dr. Wrenn's recently published article evaluating the impact of default duration elimination on exposure to fluoroquinolone therapy.  The article reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38347810/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.84 – Navigating the LAByrinth: Updates in Antibacterial Susceptibility Testing

Episode Notes

In this episode of the DASON Digest Podcast, one of our DASON Clinical Pharmacist Liaisons, Dr. Melissa Johnson, talks with Dr. Jim Lewis, ID Clinical Pharmacy Coordinator and Adjunct Associate Professor at Oregon Health & Science University Departments of Pharmacy and ID in Portland, Oregon. The material reviewed in today's podcast can be found here: https://clsi.org/standards/products/microbiology/documents/m100/

For more information about DASON, please visit: https://dason.medicine.duke.edu

Ep.83 – Incorporating Adverse Event Feedback Into Antibiotic Stewardship

Episode Notes

In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about how to incorporate adverse event feedback into antibiotic stewardship. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415083/

For more information about DASON, please visit: https://dason.medicine.duke.edu

Ep.82 – Optimizing the use of the GI Panel and strategies to improve appropriate testing

Episode Notes

In this episode, DASON Clinical Pharmacist Liaisons Drs. Jeannette Bouchard and Libby Dodds-Ashley walk us through the details of a recent article published in ASHE to assess the impact of a clinical decision support survey to improve GI Panel ordering appropriateness at a VA. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415090/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.81 – Which of Active vs Passive Response to Rapid Diagnostic Blood Culture Results

Episode Notes

In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the use of active versus passive methods of responding to rapid diagnostic blood culture results. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/36483427/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.80 – Exploring the Microbiome: Pertinent details from a phase 1 study exploring omadacycline in healthy guts

Episode Notes

In this episode, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard is joined by Dr. Kevin Garey, an adjunct professor at the University of Texas School of Public Health and senior author of the reviewed article. They walk us through the details of the microbiome effects oral omadacycline has versus oral vancomycin and what this might mean for the future of the treatment for C. difficile infections. The materials reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38051631/ and https://pubmed.ncbi.nlm.nih.gov/22563022/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.79 – It’s All in the Dose: High-dose oral beta-lactams for bacteremic UTIs due to Enterobacterales

Episode Notes

In this episode, DASON Clinical Pharmacist Liaisons Drs. Melissa Johnson and Jeannette Bouchard discuss an article from ASHE on high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/37771747/

For more information about DSAON, please visit: https://dason.medicine.duke.edu/

Ep.78 – Source Specific Sepsis Order Sets Lead to Improved Empiric Therapy in the ED

Episode Notes

In this episode, Dr. April Dyer, one of our DASON Clinical Pharmacist Liaisons, talks to us about source specific order sets leading to improved empiric therapy in the ED in a 200 bed hospital. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad677/7491622#

To learn more about DASON, please visit: https://dason.medicine.duke.edu

2020