Ep.119 – New Rules for Old Infections: What the DOTS Trial Tells Us

Episode Notes

Join DASON Clinical Pharmacist Liaison Jeannette Bouchard as she speaks with Dr. Nick Turner, lead author of the DOTS randomized clinical trial, about the potential of dalbavancin as a simplified treatment for Staphylococcus aureus bacteremia. They discuss the trial’s findings, its implications for clinical practice, and whether two doses can truly replace weeks of IV antibiotics. The materials reviewed in this episode can be found here: https://dason.medicine.duke.edu/blog/new-rules-old-infections-what-dots-trial-tells-us

For more information about DASON, please visit: https://dason.medicine.duke.edu

Ep.118 – Combatting unnecessary ASB treatment through diagnostic stewardship – which approach works?

Episode Notes

In this episode, Dr. Melissa Johnson, one of our DASON Clinical Pharmacist Liaisons, talks with Dr. Kim Claeys, from the University of Maryland, about her recent work on the implementation diagnostic stewardship to improve UTI antibiotic use. The two publications referenced in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40720743/ and here: https://pubmed.ncbi.nlm.nih.gov/37424224/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.117 – Nurse-Driven PEN-FAST Allergy De-labeling

Episode Notes

In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison, Dr. April Dyer, talks to us about an article in Antimicrobial Stewardship & Healthcare Epidemiology entitled "Implementation and performance of a nurse administered modified PEN-FAST clinical decision rule in the electronic health record." The article can be found here: https://pubmed.ncbi.nlm.nih.gov/40697885/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.116 – Cascade Reporting Under the Microscope: Two Sides, One Debate

Episode Notes

Join host DASON Clinical Pharmacist Liaison Dr. Libby Dodds Ashley as she as talks with Dr. Emily Heil and Dr. Joe Kuti to review the recent article published in the Journal of Clinical Microbiology titled: “Point-Counterpoint: Cascade Reporting—Useful Tool to Support Antimicrobial Stewardship, or Dangerously Misleading?” Together, they explore the practical and controversial aspects of cascade reporting. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40526395/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.115 – Septic Shock and AKI: Do we still need to worry about piperacillin-tazobactam?

Episode Notes

In this episode of the DASON Digest podcast, DASON clinical pharmacist liaison Dr. Angelina Davis talks with us about a national retrospective cohort study comparing the effects of cefepime versus piperacillin-tazobactam on the development of severe acute kidney injury in patients with septic shock. The article for this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/39657005/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.114 – Procalcitonin in Practice: Evaluating Its Impact on CAP Management

Episode Notes

Join DASON Liaison Jeannette Bouchard as she hosts Dr. Dan Ilges and Dr. Ryan Stevens to discuss the recent article published in Infection Control & Hospital Epidemiology titled: “Real-world Utility of Procalcitonin in Patients Hospitalized with Community-Acquired Pneumonia: A Matched Cohort Study.” Together, they unpack how this study challenges the utility of procalcitonin in guiding antibiotic use for CAP, explores implications for diagnostic stewardship, and reflects on strategies to optimize antimicrobial decision-making in inpatient care.

The articles reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40017121/ and here: https://www.fda.gov/media/100879/download

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.113 – Are You Ready for It? Assessing Cephalosporin Allergies with the CEPH-FAST Score

Episode Notes

In this episode, DASON Clinical Pharmacist Liaison Dr. Melissa Johnson talks with Dr. Jason Trubiano, Director of Infectious Diseases at Austin Health in Australia. Drs. Johnson and Trubiano discuss an article in Journal of Infection entitled "Development and validation of a cephalosporin allergy clinical decision rule." The article can be found here: https://pubmed.ncbi.nlm.nih.gov/40288499/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.112 – (Re)moving the needle: implementation of an institutional IV to PO treatment guidance for bone and joint infections

Join DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard as she reviews the recent article published in Antimicrobial Stewardship & Healthcare Epidemiology titled: (Re)Moving the Needle: A Retrospective, Quasi-Experimental Assessment of the Impact of a Treatment Guideline on Oral Antibiotic Prescribing for Orthopedic Infections." She discusses how this study highlights the real-world impact of guideline implementation on shifting antibiotic prescribing practices for bone and joint infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40160226/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

Ep.111 – Sole Support: Using Clinical Decision Support Solutions to Improve Care for Patients Inpatients with Diabetic Foot Infections

In this episode, DASON Clinical Pharmacist Liaison Dr. April Dyer talks with us about how a microbiology-driven electronic health record-algorithm and order set can decrease antipseudomonal use in diabetic foot infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/40160223/

For more information about DASON, please visit: https://dason.medicine.duke.edu/

SBP Prophylaxis: What We’re Doing, Why We’re Doing It… and Should We Keep Doing It?

Episode Notes

In this episode, DASON Clinical Pharmacist Liaison Dr. Angelina Davis chats with us about several articles about antibiotic prophylaxis for spontaneous bacterial peritonitis (SBP) in patients with cirrhosis.

The materials reviewed in this episode can be found on the DASON Digest page on our website: https://dason.medicine.duke.edu/blog/sbp-prophylaxis-what-were-doing-why-were-doing-it-and-should-we-keep-doing-it

For more information about DASON, please visit: https://dason.medicine.duke.edu/

2020